
DHM
Dihydromyricetin from Vine Tea Extract, our flagship ingredient at 1,200 mg per serving. Supports healthy liver and metabolic function.*
Supports Next-Day Performance.*
Enhances energy and mental clarity.*
12 pre-dosed packets. 4 capsules each.
5.0 · 44 reviews| DHMDihydromyricetin from Vine Tea Extract | 1,200 mg |
|---|---|
| L-GlutathioneBiologically active form | 300 mg |
| L-CysteineHCl Anhydrous | 450 mg |
Every ingredient and dose disclosed.
Supply. Build. Enable. Recycle.
Your body handles alcohol across several systems. First Round supports them in parallel.*
And at the center of that multi-pathway architecture: glutathione.
Glutathione is one of your body’s master antioxidants, the molecule your cells lean on to manage everyday oxidative stress. Your body makes its own, but levels aren’t something it can raise on the spot. That’s why First Round delivers L-Glutathione directly, in its biologically active form, then supports it across the four stages below.*
Choose a stage to pause and read.
Will not prevent intoxication. Drink responsibly.
Thirteen dietary ingredients, each chosen for a specific, complementary role.

Dihydromyricetin from Vine Tea Extract, our flagship ingredient at 1,200 mg per serving. Supports healthy liver and metabolic function.*

The biologically active form of glutathione, the body's master antioxidant. The centerpiece of the four-stage glutathione support architecture.*

A dual-function amino acid. Supports the body's own glutathione production as a key precursor and contributes to the formula's antioxidant defense.*

A group of plant antioxidants that support advanced antioxidant defense.*

Four premium B vitamins to support energy metabolism, mental clarity, and nutrient replenishment. Includes biologically active Methylcobalamin, not standard cyanocobalamin.*

Selenium as L-Selenomethionine, a premium amino-acid-bound form. Supports glutathione-related enzyme activity as part of the antioxidant support architecture.*

Patented black pepper extract standardized to 95 percent piperine. Supports polyphenol bioavailability.*
Every dose is printed on the Supplement Facts panel. Nothing hidden in a blend.
Take 4 capsules with water, 30 to 60 minutes before drinking.
Full directionsFollow label directions. Will not prevent intoxication. Drink responsibly.
Take First Round before your first drink, so your body's support systems are active from the start of the evening.
Four capsules with water before your first drink. Each serving comes pre-measured in its own packet.
First Round is already in your system as your body starts processing alcohol, working across multiple pathways at once.*
Built to support next-day performance, energy, and mental clarity, so you can get on with your day.*
Multi-ingredient support for healthy liver function, designed to be taken before your first drink.
Supply, build, enable, recycle. A four-stage glutathione support architecture.
DHM and L-Cysteine HCl Anhydrous support the body's natural processing of alcohol-related byproducts.
Essential B vitamins in meaningful doses, with premium forms.
Four botanical antioxidants supporting antioxidant defense from multiple angles.
L-Glutathione and L-Cysteine support healthy skin tone and an even, healthy complexion during and after social occasions.
Each serving comes pre-measured in its own packet: four capsules with water before your first drink.





Every ingredient and its exact dose is printed on the Supplement Facts panel. Nothing hidden in a blend. As printed on the box.
Made in the USA with globally sourced ingredients.


Pre-Drink Dietary Supplement · 12 packets · 48 capsules (4 per packet)
5.0 · 44 reviewsFrom celebrations and client dinners to conference receptions, weekend brunch or wine at home, First Round fits a range of social occasions. Explore the ingredients and how to use it before your first drink.
About First RoundStraight answers on timing, what's inside, safety and orders. The full list lives on the FAQ page.
Need help? Email support@supreme-balance.com.
Timing is everything. From your very first drink, your body gets to work processing alcohol, and that's exactly when support matters most. Take First Round 30 to 60 minutes ahead, and it's already in your system and working as that process kicks in, instead of after the fact. The idea is simple: get ahead of the night, don't chase it.*
When you drink, your body produces byproducts and burns through antioxidants and B vitamins. First Round is built to stay ahead of that, working across multiple pathways at once: supporting your body's natural processing of those byproducts, providing a four-stage glutathione support architecture, adding botanical antioxidant support, and replenishing the B vitamins your body uses up.*
It comes down to transparency and how the formula is built. Every one of the 13 ingredients is disclosed at its real dose, no proprietary blends, so you know exactly what you're paying for. And it doesn't cut corners: 1,200 mg of DHM, a four-stage glutathione support architecture, four botanical antioxidants, and a B-complex in active forms like Methylcobalamin (B12), plus selenium as L-Selenomethionine, all working across multiple pathways to support your next-day performance.*
For best results, take all 4 capsules with water 30 to 60 minutes before drinking alcohol. That's how First Round is designed to work best.
Prefer to split it? Take 2 capsules before drinking alcohol, and 2 capsules later in the evening. Do not exceed 8 capsules in 24 hours.
First Round contains no caffeine. The energy and mental clarity support comes from replenishing essential B vitamins.*
First Round is third-party tested and made in a GMP-certified facility. It is Non-GMO, Gluten-Free, Dairy-Free, and Soy-Free. If you are pregnant, nursing, taking medication, or have a medical condition, consult your healthcare provider. Will not prevent intoxication; drink responsibly.
Each box contains 12 packets, one 4-capsule serving per packet, so 12 nights out. If you're taking the 2-capsule daily routine instead, a box lasts about 24 days.
You're covered by our 30-Day Promise. If you're not satisfied for any reason, refund requests are accepted within 30 days of delivery, for your first order, up to one box. Refunds cover the product price, and shipping is always free.
Subscribe & Save ships on the schedule you choose, with free shipping, auto-renewing until you cancel. Skip, pause, or cancel anytime in your account. No call or email needed.

A premium pre-drink supplement, taken before your first drink.
